Healthy Aging at Tufts Pilot Grants 2020-2021

Project Title: Mechanisms of Drosophila lifespan extension by Parabacteriodes distasonis

Principal Investigators: Dr. Mitch McVey, A&S Biology  & Dr. Jimmy Crott, HNRCA

In this study, we will utilize molecular, and cellular imaging techniques to elucidate the mechanisms by which P.dist extends lifespan and improves healthspan in Drosophila.

Project Title: Polymorphonuclear leukocyte senescence in age-associated susceptibility to Streptococcus pneumoniae lung infection

Principal Investigator: Dr. Alexander Poltorak, TUSM Immunology

This collaborative project will use progeroid mice to assess the role of regulatory genes in age-associated inflammation and senescence.

For questions and submission of a proposal, please contact healthyaging@tufts.edu